heartsick

As adjectives the difference between distraught and heartsick

is that distraught is deeply hurt, saddened, or worried; distressed while heartsick is very despondent or sorrowful.

As adjectives the difference between heartsick and heartfelt

is that heartsick is very despondent or sorrowful while heartfelt is felt or believed deeply and sincerely.

As adjectives the difference between heartsick and heartstruck

is that heartsick is very despondent or sorrowful while heartstruck is driven to the heart; infixed in the mind.

As adjectives the difference between heartsick and downcast

is that heartsick is very despondent or sorrowful while downcast is (of eyes) looking downwards.

As a noun downcast is

(computing) a cast from supertype to subtype.

As a verb downcast is

(obsolete) to cast or throw up; to turn upward.

Offended is a related term of heartsick.

As a verb offended

is (offend).

As an adjective heartsick is

very despondent or sorrowful.

As adjectives the difference between heartsick and lovelorn

is that heartsick is very despondent or sorrowful while lovelorn is being lorn by love.

Morose is a related term of heartsick.

As adjectives the difference between morose and heartsick

is that morose is sullen]], gloomy; showing a [[brood|brooding ill humour while heartsick is very despondent or sorrowful.

As an adjective heartsick is

very despondent or sorrowful.

Miserable is a related term of heartsick.

As adjectives the difference between miserable and heartsick

is that miserable is destitute, impoverished while heartsick is very despondent or sorrowful.

As a noun miserable

is wretch, scoundrel.

As adjectives the difference between rueful and heartsick

is that rueful is causing, feeling, or expressing regret or sorrow while heartsick is very despondent or sorrowful.