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Ubiquitination vs Autoubiquitination - What's the difference?

ubiquitination | autoubiquitination |

In biochemistry|lang=en terms the difference between ubiquitination and autoubiquitination

is that ubiquitination is (biochemistry) the modification of a protein by the covalent attachment of one or more ubiquitin molecules while autoubiquitination is (biochemistry) self-ubiquitination by an ubiquitinating enzyme, usually an e3 or e4 ubiquitin ligase this activity can be direct, as in monoubiquitin of a lysine residue on the e3 or e4 itself, or indirect, through addition of ubiquitin to an existing polyubiquitin chain that is attached to the e3 or e4.

As nouns the difference between ubiquitination and autoubiquitination

is that ubiquitination is (biochemistry) the modification of a protein by the covalent attachment of one or more ubiquitin molecules while autoubiquitination is (biochemistry) self-ubiquitination by an ubiquitinating enzyme, usually an e3 or e4 ubiquitin ligase this activity can be direct, as in monoubiquitin of a lysine residue on the e3 or e4 itself, or indirect, through addition of ubiquitin to an existing polyubiquitin chain that is attached to the e3 or e4.

ubiquitination

English

Noun

(-)
  • (biochemistry) The modification of a protein by the covalent attachment of one or more ubiquitin molecules

    • Synonyms

    * ubiquitinylation

    autoubiquitination

    English

    Noun

    (-)
  • (biochemistry) Self-ubiquitination by an ubiquitinating enzyme, usually an E3 or E4 ubiquitin ligase. This activity can be direct, as in monoubiquitin of a lysine residue on the E3 or E4 itself, or indirect, through addition of ubiquitin to an existing polyubiquitin chain that is attached to the E3 or E4.

    • See also

    * polyubiquitin