despair

As nouns the difference between despair and bitterness

is that despair is loss of hope; utter hopelessness; complete despondency while bitterness is the quality of having a bitter taste.

As a verb despair

is to give up as beyond hope or expectation; to despair of.

As nouns the difference between despair and disparity

is that despair is loss of hope; utter hopelessness; complete despondency while disparity is the state of being unequal; difference.

As a verb despair

is to give up as beyond hope or expectation; to despair of.

As verbs the difference between dispirit and despair

is that dispirit is lower the morale of; make despondent; dishearten while despair is (obsolete) to give up as beyond hope or expectation; to despair of.

As a noun despair is

loss of hope; utter hopelessness; complete despondency.

As nouns the difference between ecstasy and despair

is that ecstasy is intense pleasure while despair is loss of hope; utter hopelessness; complete despondency.

As a proper noun Ecstasy

is the drug MDMA, a synthetic entactogen of the phenethylamine family.

As a verb despair is

to give up as beyond hope or expectation; to despair of.

As verbs the difference between despair and surrender

is that despair is (obsolete) to give up as beyond hope or expectation; to despair of while surrender is to give up into the power, control, or possession of another; specifically (military) to yield (a town, a fortification, etc) to an enemy.

As nouns the difference between despair and surrender

is that despair is loss of hope; utter hopelessness; complete despondency while surrender is an act of surrendering, submission into the possession of another; abandonment, resignation.

As verbs the difference between depressed and despair

is that depressed is (depress) while despair is (obsolete) to give up as beyond hope or expectation; to despair of.

As an adjective depressed

is unhappy, and blaming oneself rather than others; despondent.

As a noun despair is

loss of hope; utter hopelessness; complete despondency.

Despair is a synonym of discouragement.

As nouns the difference between despair and discouragement

is that despair is loss of hope; utter hopelessness; complete despondency while discouragement is the act of discouraging.

As a verb despair

is (obsolete) to give up as beyond hope or expectation; to despair of.

As verbs the difference between despair and deprive

is that despair is (obsolete) to give up as beyond hope or expectation; to despair of while deprive is .

As a noun despair

is loss of hope; utter hopelessness; complete despondency.

As a verb despair

is (obsolete) to give up as beyond hope or expectation; to despair of.

As a noun despair

is loss of hope; utter hopelessness; complete despondency.

As an adjective apprehensive is

.

As nouns the difference between guilt and despair

is that guilt is responsibility for wrongdoing while despair is loss of hope; utter hopelessness; complete despondency.

As verbs the difference between guilt and despair

is that guilt is to commit offenses; act criminally while despair is to give up as beyond hope or expectation; to despair of.