As adjectives the difference between skanky and skunky
is that skanky is in the manner of a skank (disreputable woman while skunky is having an unpleasant odor.
skanky
English
Adjective
(er)
in the manner of a skank (disreputable woman)
(British slang) vile
skunky
English
Adjective
(er)
having an unpleasant odor
Having a smell of skunk (a type of marijuana)