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Proteoform vs Proteiform - What's the difference?

proteoform | proteiform |

As a noun proteoform

is a specific molecular form of a protein product arising from a specific gene.

As an adjective proteiform is

(zoology) changeable in form; resembling a proteus.

proteoform

English

Noun

(s)
  • A specific molecular form of a protein product arising from a specific gene.
  • Any of a group of related protein molecules arising from all combinatorial sources of variation giving rise to products arising from a single gene. These include products differing due to genetic variation, alternatively spliced RNA, transcripts, and post-translational modifications.

    • Usage notes

    The term includes all PTMs classified by the PSI-MOD] ontology (which uses PSI-MS standardized names for protein modifications), except those classified as reagent derivatized residues ([http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00848 MOD:00848]) or isotope labeled residues ([http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00702 MOD:00702).

    References

    * http://smith.chem.wisc.edu/research/proteoforms * http://www.topdownproteomics.org * Proteoform: a single term describing protein complexity. Nat Methods. 2013 Mar;10(3):186-7. doi: 10.1038/nmeth.2369.

    proteiform

    English

    Adjective

    (en adjective)
  • (zoology) changeable in form; resembling a proteus
    • (Webster 1913)