As nouns the difference between manuscript and handbook

is that manuscript is a book, composition or any other document, written by hand (or manually typewritten), not mechanically reproduced while handbook is a topically organized book of reference on a certain field of knowledge, disregarding the size of it.

As an adjective manuscript

is handwritten, or by extension manually typewritten, as opposed to being mechanically reproduced.

As nouns the difference between manuscripts and handbook

is that manuscripts is while handbook is a topically organized book of reference on a certain field of knowledge, disregarding the size of it.

As nouns the difference between downfall and downtrend

is that downfall is a precipitous decline in fortune; death or rapid deterioration, as in status or wealth while downtrend is any gradual movement towards a lower state or value.

As a verb downfall

is to fall down; deteriorate; decline.

As a proper noun Beatles

is an extremely successful and influential British rock music quartet that operated primarily in the 1960s.

As a noun beetle is

any of numerous species of insect in the order Coleoptera characterized by a pair of hard, shell-like front wings which cover and protect a pair of rear wings when at rest.

As a verb beetle is

to move away quickly, to scurry away.

As an adjective beetle is

protruding, jutting, overhanging. (As in beetle brows..

As a proper noun beatles is

an extremely successful and influential british rock music quartet that operated primarily in the 1960s.

As nouns the difference between penguin and petrel

is that penguin is any of several flightless sea birds, of order sphenisciformes , found in the southern hemisphere; marked by their usual upright stance, walking on short legs, and (generally) their stark black and white plumage while petrel is petrel (bird).

As nouns the difference between simultaneity and synchronization

is that simultaneity is the quality or state of being simultaneous; simultaneousness while synchronization is the state or property of being synchronized.

As an adjective previous

is prior; occurring before something else, either in time or order.

As a noun previous

is an existing criminal record; short for "previous convictions".

As a verb proceeded is

past tense of proceed.

As an adjective immemorial

is immemorial, age-old.

As a noun old is

age.

As adjectives the difference between analog and simulate

is that analog is in which the value of a data item (such as time) is represented by a continuously variable physical quantity that can be measured (such as the shadow of a sundial while simulate is feigned; pretended.

As a noun analog

is something that bears an analogy to something else.

As a verb simulate is

to model, replicate, duplicate the behavior, appearance or properties of.