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Inoculation vs Variolation - What's the difference?

inoculation | variolation |

As nouns the difference between inoculation and variolation

is that inoculation is the introduction of an antigenic substance or vaccine into the body to produce immunity to a specific disease while variolation is the inoculation of a person with smallpox so as to induce a mild form of the illness and subsequent immunity to it.

inoculation

Noun

(en noun)
  • (immunology) The introduction of an antigenic substance or vaccine into the body to produce immunity to a specific disease.
  • (microbiology) The introduction of a microorganism into a culture medium.
  • An inoculum, what is inoculated
  • See also

    * immunisation * vaccination

    variolation

    English

    Noun

    (en noun)
  • (historical) The inoculation of a person with smallpox so as to induce a mild form of the illness and subsequent immunity to it.