Howsoever vs Whosoever - What's the difference?

Whosoever is a anagram of howsoever.

is in any manner whatsoever.

whichever person; whoever.

(head)

In any manner whatsoever.

To whatever degree or extent; however.

* whosoever

(en-pron)

whichever person; whoever

* 1597 — v 3

If thou do pardon, whosoever pray,
More sins for this forgiveness prosper may.

* 1611 — 6:47

*:"Whosoever cometh to me, and heareth my sayings, and doeth them, I will shew you to whom he is like"

* 18?? — , source?

This world, after all our science and sciences, is still a miracle wonderful, inscrutable, magical and more, to whosoever will think of it.

* howsoever