As nouns the difference between histone and deacetyltransferase

is that histone is (biochemistry) any of various simple water soluble proteins that are rich in the basic amino acids lysine and arginine and are complexed with dna in the nucleosomes of eukaryotic chromatin while deacetyltransferase is (enzyme) any of a class of enzymes that remove acetyl groups, especially from a lysine residue of a histone.