Porphyria vs Heme - What's the difference?
porphyria | heme |
(pathology) Any of several usually hereditary abnormalities of porphyrin metabolism characterized by excretion of excess porphyrins in the urine.
* 2000', Herbert L. Bonkovsky, Richard W. Lambrecht, ''44: Hemochromatosis, iron overload, and '''porphyria cutanea tarda'', James C. Barton, Corwin Q. Edwards (editors), ''Hemochromatosis: Genetics, Pathophysiology, Diagnosis and Treatment ,
* 2003', M. Lecha, C. Herrero, D. Ozalla, '''''Porphyrias'' , Andreas D. Katsambas, Torello M. Lotti (editors), ''European Handbook of Dermatological Treatments ,
* 2010 , James C. Barton, Corwin Q. Edwards, Pradyumna D. Phatak, Robert S. Britton, Bruce R. Bacon, Handbook of Iron Overload Disorders ,
The component of hemoglobin (and other hemoproteins) responsible for binding oxygen, consists of an iron ion that binds oxygen and a porphyrin ring that binds the globin molecules; one molecule binds one molecule of oxygen.
* 2008 , John Greer, John Foerster, George Rodgers, Fixos Paraskevas, Bertil Glader, Daniel Arber, Robert Means Jr, Wintrobe's Clinical Hematology: Volume One: Twelfth Edition , page 141:
As nouns the difference between porphyria and heme
is that porphyria is (pathology) any of several usually hereditary abnormalities of porphyrin metabolism characterized by excretion of excess porphyrins in the urine while heme is heme / haem.porphyria
English
Noun
(en noun)page 453,
- The term porphyria'', derived from the Greek word ''porphyra , meaning purple, is apt because a hallmark of most of the porphyrias is the overexcretion of porphyrins in urine or feces.
page 419,
- However, the appearance of homozygous forms without consanguinity and coincidence of two types of porphyria' in the same patient, dual ' porphyrias , is possible.
page 160,
- The usual presenting symptoms and signs of porphyrias are either skin photosensitivity or neurovisceral symptoms and signs.
Derived terms
* porphyricheme
English
Alternative forms
* haem (British )Noun
- The binding of oxygen to the iron molecule causes the hemoglobin molecule to undergo conformational changes that affect the binding of oxygen to other heme sites.