As nouns the difference between methadone and blog
is that methadone
is (chemistry) a synthetic opioid analgesic, used to wean addicts off of heroin or other opiate based narcotics, and in chronic pain management while blog
is (internet) a website that allows users to reflect, share opinions, and discuss various topics in the form of an online journal, sometimes letting readers comment on their posts most blogs are written in a slightly informal tone (personal journals, news, businesses, etc) entries typically appear in reverse chronological order or blog
can be (dated|fandom slang|jocular).
As a verb blog is
(blogging) to contribute to a blog or blog
can be (british|slang) to blag, to steal something; to acquire something illegally.