manuscript

As nouns the difference between manuscript and rubrication

is that manuscript is a book, composition or any other document, written by hand (or manually typewritten), not mechanically reproduced while rubrication is a form of calligraphy, in medieval manuscripts, in which added text was coloured in red.

As an adjective manuscript

is handwritten, or by extension manually typewritten, as opposed to being mechanically reproduced.

As nouns the difference between manuscript and chrysography

is that manuscript is a book, composition or any other document, written by hand (or manually typewritten), not mechanically reproduced while chrysography is the use of gold lettering in manuscripts.

As an adjective manuscript

is handwritten, or by extension manually typewritten, as opposed to being mechanically reproduced.