As a noun antidisestablishmentarianism
is a political philosophy opposed to the separation of a religious group ("church") and a government ("state"), especially the belief held by those in 19th century england opposed to separating the anglican church from the civil government or to refer to separation of church and state.
As a proper noun isis is
a sunni jihadist group active in iraq and syria, where it has proclaimed an (unrecognized) state.