despond

As a verb despond

is to give up the will, courage, or spirit; to become dejected, lose heart.

As a noun despond

is (archaic) despondency.

As an adjective despondent is

in low spirits from loss of hope or courage.

As verbs the difference between hearten and despond

is that hearten is to give heart to; to encourage, urge on, cheer, give confidence to while despond is to give up the will, courage, or spirit; to become dejected, lose heart.

As a noun despond is

(archaic) despondency.

As a verb despond

is to give up the will, courage, or spirit; to become dejected, lose heart.

As a noun despond

is (archaic) despondency.

As an adjective desperate is

being filled with, or in a state of despair; hopeless.

As nouns the difference between heartsickness and despond

is that heartsickness is the condition of being heartsick while despond is (archaic) despondency.

As a verb despond is

to give up the will, courage, or spirit; to become dejected, lose heart.

As verbs the difference between disappoint and despond

is that disappoint is to displease by e.g. underperforming while despond is to give up the will, courage, or spirit; to become dejected, lose heart.

As a noun despond is

despondency.

As verbs the difference between deject and despond

is that deject is make sad or dispirited while despond is to give up the will, courage, or spirit; to become dejected, lose heart.

As a noun despond is

despondency.

As nouns the difference between despond and despondence

is that despond is (archaic) despondency while despondence is the state of being downcast or despondent.

As a verb despond

is to give up the will, courage, or spirit; to become dejected, lose heart.

As nouns the difference between downcast and despond

is that downcast is (computing) a cast from supertype to subtype while despond is (archaic) despondency.

As verbs the difference between downcast and despond

is that downcast is (obsolete) to cast or throw up; to turn upward while despond is to give up the will, courage, or spirit; to become dejected, lose heart.

As an adjective downcast

is (of eyes) looking downwards.

As verbs the difference between despond and depress

is that despond is to give up the will, courage, or spirit; to become dejected, lose heart while depress is to press down.

As a noun despond

is (archaic) despondency.

Despond is a related term of dispair.

As verbs the difference between despond and dispair

is that despond is to give up the will, courage, or spirit; to become dejected, lose heart while dispair is to separate (a pair).

As a noun despond

is (archaic) despondency.