As adjectives the difference between atopical and atypical
is that atopical is atopic; relating to or having atopy or atopical can be not topical; untopical while atypical is not conforming to the normal type.
As a noun atypical is
(pharmacy) an atypical antipsychotic.
atopical
English
Etymology 1
Adjective
(
en adjective)
Atopic; relating to or having atopy.
Etymology 2
atypical
English
Adjective
(
en adjective)
Not conforming to the normal type.
Unusual or irregular.
Noun
(
en noun)
(pharmacy) An atypical antipsychotic.