Artemisinin vs Dihydroartemisinin - What's the difference?
artemisinin | dihydroartemisinin |
(medicine, biochemistry, organic compound) An antimalarial drug derived from the (sweet wormwood) shrub, , found as the active ingredient in traditional Chinese medical herbal treatment for malaria, chemically a sesquiterpene lactone; a group of compounds chemically related to the drug.
* 1994' May, Mankil Jung, ''Current Developments in the Chemistry of '''Artemisinin and Related Compounds'', ''Current Medicinal Chemistry ,
* 1998', Dee Ann Casteel, ''Synthesis of Simple Bridged Bicyclic Trioxanes as Analogs of the Antimalarial Natural Product, '''Atemisinin'' , Attaur Rahman (editor), ''New Trends in Natural Product ,
* 2010 , Bill Shore, The Imaginations of Unreasonable Men ,
An antimalarial drug, the active metabolite of all artemisinin compounds, also available as a drug in itself.
As nouns the difference between artemisinin and dihydroartemisinin
is that artemisinin is an antimalarial drug derived from the sweet wormwood shrub, species: Artemisia annua, found as the active ingredient in traditional Chinese medical herbal treatment for malaria, chemically a sesquiterpene lactone; a group of compounds chemically related to the drug while dihydroartemisinin is an antimalarial drug, the active metabolite of all artemisinin compounds, also available as a drug in itself.artemisinin
English
(wikipedia artemisinin)Noun
(-)page 35,
- Artemisinin (Qinghaosu) isolated from Artemisia annua is a novel sesquiterpene lactone bearing an unusual endoperoxide function.
page 30,
- The practical value of artemisinin' itself as a therapeutic agent has been limited by several factors, however. ' Artemisinin has a high rate of recrudescence [8], poor oral activity [8], a short half-life in plasma [9], and limited solubility in both water and oil [10].
page 222,
- The emerging resistance to artemisinin is partly due to the complexity of the parasite and the unstoppable nature of its ability to evolve. But it is also the direct result of greed, for which there is no drug or vaccine.
- In early 2009 the World Health Organization (WHO) announced the discovery of malaria parasites along the Thai-Cambodia border that were proving resistant to commonly used derivatives of artemisinin called artesunate and anthemeter.
