(biochemistry, genetics) A base, C5H5N5, found in certain glands and tissues, which pairs with thymine in DNA and uracil in RNA.
* 2002 , Nikolai L. Vekshin, Photonics of Biopolymers ,
* 2006 , David Markie, 1: Markers, Selection, and Media in Yeast Artificial Chromosome Cloning'', Alasdair MacKenzie (editor), ''YAC Protocols , 2nd Edition,
- One of these labels is ethenoadenine, which is obtained by chemical modification of adenine .
* 2010', Debjani Roy, Rogué Schleyer, ''6: Chemical Origin of Life: How do Five HCN Molecules Combine to form '''Adenine under Prebiotic and Interstellar Conditions'', Chérif F. Matta, ''Quantum Biochemistry ,
- There are two genes in the adenine' biosynthetic pathway of yeast (''ADE1'' and ''ADE2'') that, apart from producing an absolute requirement for ' adenine when mutant, also produce a change in colony color.
- The HCN pentamer, adenine (a constituent of DNA, RNA and many coenzymes), is one of the most abundant biochemical molecules.
(organic compound) Any of a class of organic heterocyclic compounds composed of fused pyrimidine and imidazole rings that comprise one of the two groups of organic nitrogenous bases (the other being the pyrimidines) and are components of nucleic acids.
* 1982 , Ray A. Field, Mechanically Deboned Red Meat'', C. O. Chichester, George Franklin Stewart, ''Advances in Food Research , Volume 27,
* 1993 , Andrew Travers, DNA-Protein Interactions ,
- Clifford et al.'' (1976) investigated the metabolism of individual purines''' and found that adenine, and to a lesser extent hypoxanthine, had pronounced effects on blood uric acid levels. The ' purine content of foods, in particular adenine, would therefore be of immense nutritional significance.
* 2008 , Hemanta K. Majumder, Drug Targets in Kinetoplastid Parasites ,
- For example, for purine'-pyrimidine and for pyrimidine-'''purine''' base steps the presence of ' purines on opposite strands in successive base pairs sterically restricts the conformations that these base pairs can adopt relative to each other.
- The discovery that certain pyrazolopyrimidine nucleobases and nucleosides, analogs of naturally occurring purines', are toxic to ''Leishmania'', coupled with the obligatory nature of the leishmanial '''purine''' salvage pathway, has spawned considerable interest in the ' purine salvage pathway as a drug target.
* uric acid